BDBM50127836 2-[2-(3-Piperidin-1-yl-propoxy)-phenyl]-indolizine::CHEMBL49723

SMILES: C(COc1ccccc1-c1cc2ccccn2c1)CN1CCCCC1

InChI Key: InChIKey=OGQKJZPIDFFUTC-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127836   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50127836 (2-[2-(3-Piperidin-1-yl-propoxy)-phenyl]-indolizine...) Show SMILES C(COc1ccccc1-c1cc2ccccn2c1)CN1CCCCC1 Show InChI InChI=1S/C22H26N2O/c1-5-12-23(13-6-1)14-8-16-25-22-11-3-2-10-21(22)19-17-20-9-4-7-15-24(20)18-19/h2-4,7,9-11,15,17-18H,1,5-6,8,12-14,16H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	236	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Botswana Curated by ChEMBL					Assay Description Antagonist activity at human histamine H3 receptor				Eur J Med Chem 46: 5237-57 (2011) Article DOI: 10.1016/j.ejmech.2011.08.042 BindingDB Entry DOI: 10.7270/Q2ZG6SNF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50127836 (2-[2-(3-Piperidin-1-yl-propoxy)-phenyl]-indolizine...) Show SMILES C(COc1ccccc1-c1cc2ccccn2c1)CN1CCCCC1 Show InChI InChI=1S/C22H26N2O/c1-5-12-23(13-6-1)14-8-16-25-22-11-3-2-10-21(22)19-17-20-9-4-7-15-24(20)18-19/h2-4,7,9-11,15,17-18H,1,5-6,8,12-14,16H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	236	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development L. L. C. Curated by ChEMBL					Assay Description Binding affinity towards human Histamine H3 receptor using [3H]-N-methyl-histamine as radioligand				Bioorg Med Chem Lett 13: 1767-70 (2003) BindingDB Entry DOI: 10.7270/Q21835V3
					More data for this Ligand-Target Pair