BDBM50127839 1-Methanesulfonyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-1H-indole::CHEMBL51877
SMILES: CS(=O)(=O)n1c(cc2ccccc12)-c1ccc(OCCCN2CCCCC2)cc1
InChI Key: InChIKey=VFWZPAGPEKHOAE-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50127839 (1-Methanesulfonyl-2-[4-(3-piperidin-1-yl-propoxy)-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development L. L. C. Curated by ChEMBL | Assay Description Binding affinity towards human Histamine H3 receptor using [3H]-N-methyl-histamine as radioligand | Bioorg Med Chem Lett 13: 1767-70 (2003) BindingDB Entry DOI: 10.7270/Q21835V3 | |||||||||||
More data for this Ligand-Target Pair |