BDBM50128019 1-(2,6-Difluoro-benzyl)-6-methyl-3-{2-[methyl-(2-pyridin-2-yl-ethyl)-amino]-ethyl}-5-(4-phenoxy-phenyl)-1H-pyrimidine-2,4-dione::1-(2,6-difluorobenzyl)-6-methyl-3-(2-(methyl(2-(pyridin-2-yl)ethyl)amino)ethyl)-5-(4-phenoxyphenyl)pyrimidine-2,4(1H,3H)-dione::CHEMBL60153

SMILES: CN(CCc1ccccn1)CCn1c(=O)c(c(C)n(Cc2c(F)cccc2F)c1=O)-c1ccc(Oc2ccccc2)cc1

InChI Key: InChIKey=LNGXWTLFKRGUFX-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50128019   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin releasing hormone 1 (GnRHR1) (Homo sapiens (Human))	BDBM50128019 (1-(2,6-Difluoro-benzyl)-6-methyl-3-{2-[methyl-(2-p...) Show SMILES CN(CCc1ccccn1)CCn1c(=O)c(c(C)n(Cc2c(F)cccc2F)c1=O)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C34H32F2N4O3/c1-24-32(25-14-16-28(17-15-25)43-27-10-4-3-5-11-27)33(41)39(22-21-38(2)20-18-26-9-6-7-19-37-26)34(42)40(24)23-29-30(35)12-8-13-31(29)36/h3-17,19H,18,20-23H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity at human GnRH receptor				J Med Chem 51: 3331-48 (2008) Article DOI: 10.1021/jm701249f BindingDB Entry DOI: 10.7270/Q2KD1XQ0
					More data for this Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1) (Homo sapiens (Human))	BDBM50128019 (1-(2,6-Difluoro-benzyl)-6-methyl-3-{2-[methyl-(2-p...) Show SMILES CN(CCc1ccccn1)CCn1c(=O)c(c(C)n(Cc2c(F)cccc2F)c1=O)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C34H32F2N4O3/c1-24-32(25-14-16-28(17-15-25)43-27-10-4-3-5-11-27)33(41)39(22-21-38(2)20-18-26-9-6-7-19-37-26)34(42)40(24)23-29-30(35)12-8-13-31(29)36/h3-17,19H,18,20-23H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity was determined towards human gonadotropin-releasing hormone receptor				J Med Chem 46: 2023-6 (2003) Article DOI: 10.1021/jm034041s BindingDB Entry DOI: 10.7270/Q20864QQ
					More data for this Ligand-Target Pair