BDBM50128180 1,1,1-Trifluoro-3-{[3-(2-nitro-phenoxy)-phenyl]-[3-(1,1,2,2-tetrafluoro-ethoxy)-benzyl]-amino}-propan-2-ol::1,1,1-trifluoro-3-((3-(2-nitrophenoxy)phenyl)(3-(1,1,2,2-tetrafluoroethoxy)benzyl)amino)propan-2-ol::3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(2-nitrophenoxy)phenyl)amino)-1,1,1-trifluoropropan-2-ol::CHEMBL69187

SMILES: OC(CN(Cc1cccc(OC(F)(F)C(F)F)c1)c1cccc(Oc2ccccc2[N+]([O-])=O)c1)C(F)(F)F

InChI Key: InChIKey=IBGWYQVCWCVNRF-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50128180   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50128180 (1,1,1-Trifluoro-3-{[3-(2-nitro-phenoxy)-phenyl]-[3...) Show SMILES OC(CN(Cc1cccc(OC(F)(F)C(F)F)c1)c1cccc(Oc2ccccc2[N+]([O-])=O)c1)C(F)(F)F Show InChI InChI=1S/C24H19F7N2O5/c25-22(26)24(30,31)38-18-8-3-5-15(11-18)13-32(14-21(34)23(27,28)29)16-6-4-7-17(12-16)37-20-10-2-1-9-19(20)33(35)36/h1-12,21-22,34H,13-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Discovery Research (Pfizer Global Research and Development) Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in buffer				J Med Chem 46: 2152-68 (2003) Article DOI: 10.1021/jm020528+ BindingDB Entry DOI: 10.7270/Q2QV3KWK
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Oryctolagus cuniculus)	BDBM50128180 (1,1,1-Trifluoro-3-{[3-(2-nitro-phenoxy)-phenyl]-[3...) Show SMILES OC(CN(Cc1cccc(OC(F)(F)C(F)F)c1)c1cccc(Oc2ccccc2[N+]([O-])=O)c1)C(F)(F)F Show InChI InChI=1S/C24H19F7N2O5/c25-22(26)24(30,31)38-18-8-3-5-15(11-18)13-32(14-21(34)23(27,28)29)16-6-4-7-17(12-16)37-20-10-2-1-9-19(20)33(35)36/h1-12,21-22,34H,13-14H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Al-Zaytoonah Private University of Jordan Curated by ChEMBL					Assay Description Inhibition of CETP in rabbit serum after 1 hr by fluorescent cholesteryl esters transfer assay				Eur J Med Chem 45: 1598-617 (2010) Article DOI: 10.1016/j.ejmech.2009.12.070 BindingDB Entry DOI: 10.7270/Q2VQ32VS
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50128180 (1,1,1-Trifluoro-3-{[3-(2-nitro-phenoxy)-phenyl]-[3...) Show SMILES OC(CN(Cc1cccc(OC(F)(F)C(F)F)c1)c1cccc(Oc2ccccc2[N+]([O-])=O)c1)C(F)(F)F Show InChI InChI=1S/C24H19F7N2O5/c25-22(26)24(30,31)38-18-8-3-5-15(11-18)13-32(14-21(34)23(27,28)29)16-6-4-7-17(12-16)37-20-10-2-1-9-19(20)33(35)36/h1-12,21-22,34H,13-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal da Bahia Curated by ChEMBL					Assay Description Inhibition of CETP				Bioorg Med Chem 15: 6242-52 (2007) Article DOI: 10.1016/j.bmc.2007.06.021 BindingDB Entry DOI: 10.7270/Q2B857VG
					More data for this Ligand-Target Pair