BDBM50128400 2-Phenyl-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-1,2,3,4-tetrahydro-quinolin-6-ol::CHEMBL60538

SMILES: Oc1ccc2N(Cc3ccc(OCCN4CCCCC4)cc3)C(CCc2c1)c1ccccc1

InChI Key: InChIKey=OQJYJENHHOZHPV-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50128400   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM50128400 (2-Phenyl-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-1,...) Show SMILES Oc1ccc2N(Cc3ccc(OCCN4CCCCC4)cc3)C(CCc2c1)c1ccccc1 Show InChI InChI=1S/C29H34N2O2/c32-26-12-16-29-25(21-26)11-15-28(24-7-3-1-4-8-24)31(29)22-23-9-13-27(14-10-23)33-20-19-30-17-5-2-6-18-30/h1,3-4,7-10,12-14,16,21,28,32H,2,5-6,11,15,17-20,22H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for estrogen receptor alpha				Bioorg Med Chem Lett 13: 1907-10 (2003) BindingDB Entry DOI: 10.7270/Q2K35T16
					More data for this Ligand-Target Pair
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM50128400 (2-Phenyl-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-1,...) Show SMILES Oc1ccc2N(Cc3ccc(OCCN4CCCCC4)cc3)C(CCc2c1)c1ccccc1 Show InChI InChI=1S/C29H34N2O2/c32-26-12-16-29-25(21-26)11-15-28(24-7-3-1-4-8-24)31(29)22-23-9-13-27(14-10-23)33-20-19-30-17-5-2-6-18-30/h1,3-4,7-10,12-14,16,21,28,32H,2,5-6,11,15,17-20,22H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for estrogen receptor beta				Bioorg Med Chem Lett 13: 1907-10 (2003) BindingDB Entry DOI: 10.7270/Q2K35T16
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50128400 (2-Phenyl-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-1,...) Show SMILES Oc1ccc2N(Cc3ccc(OCCN4CCCCC4)cc3)C(CCc2c1)c1ccccc1 Show InChI InChI=1S/C29H34N2O2/c32-26-12-16-29-25(21-26)11-15-28(24-7-3-1-4-8-24)31(29)22-23-9-13-27(14-10-23)33-20-19-30-17-5-2-6-18-30/h1,3-4,7-10,12-14,16,21,28,32H,2,5-6,11,15,17-20,22H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of estradiol-stimulated MCF-7 breast adenocarcinoma cell proliferation				Bioorg Med Chem Lett 13: 1907-10 (2003) BindingDB Entry DOI: 10.7270/Q2K35T16
					More data for this Ligand-Target Pair