BDBM50128403 2-(4-Hydroxy-phenyl)-1-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-1,2,3,4-tetrahydro-quinolin-6-ol::CHEMBL293297

SMILES: Oc1ccc(cc1)C1CCc2cc(O)ccc2N1c1ccc(OCCN2CCCCC2)cc1

InChI Key: InChIKey=DYVRNYHOABJFGS-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50128403   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM50128403 (2-(4-Hydroxy-phenyl)-1-[4-(2-piperidin-1-yl-ethoxy...) Show SMILES Oc1ccc(cc1)C1CCc2cc(O)ccc2N1c1ccc(OCCN2CCCCC2)cc1 Show InChI InChI=1S/C28H32N2O3/c31-24-9-4-21(5-10-24)27-14-6-22-20-25(32)11-15-28(22)30(27)23-7-12-26(13-8-23)33-19-18-29-16-2-1-3-17-29/h4-5,7-13,15,20,27,31-32H,1-3,6,14,16-19H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for estrogen receptor alpha				Bioorg Med Chem Lett 13: 1907-10 (2003) BindingDB Entry DOI: 10.7270/Q2K35T16
					More data for this Ligand-Target Pair
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM50128403 (2-(4-Hydroxy-phenyl)-1-[4-(2-piperidin-1-yl-ethoxy...) Show SMILES Oc1ccc(cc1)C1CCc2cc(O)ccc2N1c1ccc(OCCN2CCCCC2)cc1 Show InChI InChI=1S/C28H32N2O3/c31-24-9-4-21(5-10-24)27-14-6-22-20-25(32)11-15-28(22)30(27)23-7-12-26(13-8-23)33-19-18-29-16-2-1-3-17-29/h4-5,7-13,15,20,27,31-32H,1-3,6,14,16-19H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for estrogen receptor beta				Bioorg Med Chem Lett 13: 1907-10 (2003) BindingDB Entry DOI: 10.7270/Q2K35T16
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50128403 (2-(4-Hydroxy-phenyl)-1-[4-(2-piperidin-1-yl-ethoxy...) Show SMILES Oc1ccc(cc1)C1CCc2cc(O)ccc2N1c1ccc(OCCN2CCCCC2)cc1 Show InChI InChI=1S/C28H32N2O3/c31-24-9-4-21(5-10-24)27-14-6-22-20-25(32)11-15-28(22)30(27)23-7-12-26(13-8-23)33-19-18-29-16-2-1-3-17-29/h4-5,7-13,15,20,27,31-32H,1-3,6,14,16-19H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of estradiol-stimulated MCF-7 breast adenocarcinoma cell proliferation				Bioorg Med Chem Lett 13: 1907-10 (2003) BindingDB Entry DOI: 10.7270/Q2K35T16
					More data for this Ligand-Target Pair