BDBM50128546 (3S,10R,13R)-3-Hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,17-tetradecahydro-cyclopenta[a]phenanthren-16-one oxime::CHEMBL305941

SMILES: C[C@@]12CC(CC1C1CC=C3C[C@@H](O)CC[C@]3(C)C1CC2)N=O

InChI Key: InChIKey=DKWNIVQBEHCXFU-DFYIQXLESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128546   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 17A1 (Homo sapiens (Human))	BDBM50128546 ((3S,10R,13R)-3-Hydroxy-10,13-dimethyl-1,2,3,4,7,8,...) Show SMILES C[C@@]12CC(CC1C1CC=C3C[C@@H](O)CC[C@]3(C)C1CC2)N=O |t:9| Show InChI InChI=1S/C19H29NO2/c1-18-7-6-16-15(17(18)10-13(11-18)20-22)4-3-12-9-14(21)5-8-19(12,16)2/h3,13-17,21H,4-11H2,1-2H3/t13?,14-,15?,16?,17?,18+,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	628	n/a	n/a	n/a	n/a	n/a	n/a
Accelrys Curated by ChEMBL					Assay Description In vitro cytochrome P450 17A1 inhibition was assayed using the rapid acetic acid releasing assay (AARA), utilizing intact P450c17-expressing Escheric...				J Med Chem 46: 2345-51 (2003) Article DOI: 10.1021/jm020576u BindingDB Entry DOI: 10.7270/Q2WD41B7
					More data for this Ligand-Target Pair