BDBM50128554 1-(2,6-Dichloro-phenyl)-2-(2,4-dichloro-phenyl)-3-imidazol-1-yl-propan-2-ol::CHEMBL77990

SMILES: OC(Cc1c(Cl)cccc1Cl)(Cn1ccnc1)c1ccc(Cl)cc1Cl

InChI Key: InChIKey=VOMUQNXFGYULRB-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128554   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 17A1 (Homo sapiens (Human))	BDBM50128554 (1-(2,6-Dichloro-phenyl)-2-(2,4-dichloro-phenyl)-3-...) Show SMILES OC(Cc1c(Cl)cccc1Cl)(Cn1ccnc1)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C18H14Cl4N2O/c19-12-4-5-14(17(22)8-12)18(25,10-24-7-6-23-11-24)9-13-15(20)2-1-3-16(13)21/h1-8,11,25H,9-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	610	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Accelrys Curated by ChEMBL					Assay Description In vitro inhibition of human Cytochrome P450 17A1 activity				J Med Chem 46: 2345-51 (2003) Article DOI: 10.1021/jm020576u BindingDB Entry DOI: 10.7270/Q2WD41B7
					More data for this Ligand-Target Pair