BDBM50128634 1-Cyclooctyl-4-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide::1-cyclooctyl-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide::CHEMBL81763

SMILES: COc1ccc(cc1)S(=O)(=O)C1(CCN(CC1)C1CCCCCCC1)C(=O)NO

InChI Key: InChIKey=GJICTISPMDMSQH-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50128634   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50128634 (1-Cyclooctyl-4-(4-methoxy-benzenesulfonyl)-piperid...) Show SMILES COc1ccc(cc1)S(=O)(=O)C1(CCN(CC1)C1CCCCCCC1)C(=O)NO Show InChI InChI=1S/C21H32N2O5S/c1-28-18-9-11-19(12-10-18)29(26,27)21(20(24)22-25)13-15-23(16-14-21)17-7-5-3-2-4-6-8-17/h9-12,17,25H,2-8,13-16H2,1H3,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloprotease-1				J Med Chem 46: 2376-96 (2003) Article DOI: 10.1021/jm0205550 BindingDB Entry DOI: 10.7270/Q2N0178C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50128634 (1-Cyclooctyl-4-(4-methoxy-benzenesulfonyl)-piperid...) Show SMILES COc1ccc(cc1)S(=O)(=O)C1(CCN(CC1)C1CCCCCCC1)C(=O)NO Show InChI InChI=1S/C21H32N2O5S/c1-28-18-9-11-19(12-10-18)29(26,27)21(20(24)22-25)13-15-23(16-14-21)17-7-5-3-2-4-6-8-17/h9-12,17,25H,2-8,13-16H2,1H3,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloprotease-13.				J Med Chem 46: 2376-96 (2003) Article DOI: 10.1021/jm0205550 BindingDB Entry DOI: 10.7270/Q2N0178C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50128634 (1-Cyclooctyl-4-(4-methoxy-benzenesulfonyl)-piperid...) Show SMILES COc1ccc(cc1)S(=O)(=O)C1(CCN(CC1)C1CCCCCCC1)C(=O)NO Show InChI InChI=1S/C21H32N2O5S/c1-28-18-9-11-19(12-10-18)29(26,27)21(20(24)22-25)13-15-23(16-14-21)17-7-5-3-2-4-6-8-17/h9-12,17,25H,2-8,13-16H2,1H3,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloprotease-9.				J Med Chem 46: 2376-96 (2003) Article DOI: 10.1021/jm0205550 BindingDB Entry DOI: 10.7270/Q2N0178C
					More data for this Ligand-Target Pair