BDBM50128665 4-(4-Butoxy-benzenesulfonyl)-1-methyl-piperidine-4-carboxylic acid hydroxyamide::4-(4-butoxyphenylsulfonyl)-N-hydroxy-1-methylpiperidine-4-carboxamide::CHEMBL419648

SMILES: CCCCOc1ccc(cc1)S(=O)(=O)C1(CCN(C)CC1)C(=O)NO

InChI Key: InChIKey=NLPICQLAIKGJBE-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50128665   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50128665 (4-(4-Butoxy-benzenesulfonyl)-1-methyl-piperidine-4...) Show SMILES CCCCOc1ccc(cc1)S(=O)(=O)C1(CCN(C)CC1)C(=O)NO Show InChI InChI=1S/C17H26N2O5S/c1-3-4-13-24-14-5-7-15(8-6-14)25(22,23)17(16(20)18-21)9-11-19(2)12-10-17/h5-8,21H,3-4,9-13H2,1-2H3,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloprotease-1				J Med Chem 46: 2376-96 (2003) Article DOI: 10.1021/jm0205550 BindingDB Entry DOI: 10.7270/Q2N0178C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50128665 (4-(4-Butoxy-benzenesulfonyl)-1-methyl-piperidine-4...) Show SMILES CCCCOc1ccc(cc1)S(=O)(=O)C1(CCN(C)CC1)C(=O)NO Show InChI InChI=1S/C17H26N2O5S/c1-3-4-13-24-14-5-7-15(8-6-14)25(22,23)17(16(20)18-21)9-11-19(2)12-10-17/h5-8,21H,3-4,9-13H2,1-2H3,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloprotease-9.				J Med Chem 46: 2376-96 (2003) Article DOI: 10.1021/jm0205550 BindingDB Entry DOI: 10.7270/Q2N0178C
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50128665 (4-(4-Butoxy-benzenesulfonyl)-1-methyl-piperidine-4...) Show SMILES CCCCOc1ccc(cc1)S(=O)(=O)C1(CCN(C)CC1)C(=O)NO Show InChI InChI=1S/C17H26N2O5S/c1-3-4-13-24-14-5-7-15(8-6-14)25(22,23)17(16(20)18-21)9-11-19(2)12-10-17/h5-8,21H,3-4,9-13H2,1-2H3,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	594	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro inhibitory activity against tumor necrosis factor alpha converting enzyme (TACE).				J Med Chem 46: 2376-96 (2003) Article DOI: 10.1021/jm0205550 BindingDB Entry DOI: 10.7270/Q2N0178C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50128665 (4-(4-Butoxy-benzenesulfonyl)-1-methyl-piperidine-4...) Show SMILES CCCCOc1ccc(cc1)S(=O)(=O)C1(CCN(C)CC1)C(=O)NO Show InChI InChI=1S/C17H26N2O5S/c1-3-4-13-24-14-5-7-15(8-6-14)25(22,23)17(16(20)18-21)9-11-19(2)12-10-17/h5-8,21H,3-4,9-13H2,1-2H3,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloprotease-13.				J Med Chem 46: 2376-96 (2003) Article DOI: 10.1021/jm0205550 BindingDB Entry DOI: 10.7270/Q2N0178C
					More data for this Ligand-Target Pair