BDBM50128680 CHEMBL80903::N-(1-Benzyl-2-oxo-ethyl)-2-(2-naphthalen-1-yl-vinyl)-benzamide

SMILES: O=CC(Cc1ccccc1)NC(=O)c1ccccc1\C=C\c1cccc2ccccc12

InChI Key: InChIKey=UAHDGOJUTHMOTA-ISLYRVAYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128680   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calpain1 (Homo sapiens (Human))	BDBM50128680 (CHEMBL80903 | N-(1-Benzyl-2-oxo-ethyl)-2-(2-naphth...) Show SMILES O=CC(Cc1ccccc1)NC(=O)c1ccccc1\C=C\c1cccc2ccccc12 Show InChI InChI=1S/C28H23NO2/c30-20-25(19-21-9-2-1-3-10-21)29-28(31)27-16-7-5-12-24(27)18-17-23-14-8-13-22-11-4-6-15-26(22)23/h1-18,20,25H,19H2,(H,29,31)/b18-17+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott GmbH & Co. KG Curated by ChEMBL					Assay Description Inhibitory activity against human Calpain 1 isolated from erythrocytes				J Med Chem 46: 2404-12 (2003) Article DOI: 10.1021/jm0210717 BindingDB Entry DOI: 10.7270/Q28P5ZVP
					More data for this Ligand-Target Pair