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SMILES: CCCCN(CC)c1cc(C)nc2N(CC(=O)Nc12)c1ccc(Br)cc1Br

InChI Key: InChIKey=KCWLXDNHGXTOTM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128760   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50128760
PNG
(CHEMBL3628728)
Show SMILES CCCCN(CC)c1cc(C)nc2N(CC(=O)Nc12)c1ccc(Br)cc1Br
Show InChI InChI=1S/C20H24Br2N4O/c1-4-6-9-25(5-2)17-10-13(3)23-20-19(17)24-18(27)12-26(20)16-8-7-14(21)11-15(16)22/h7-8,10-11H,4-6,9,12H2,1-3H3,(H,24,27)
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Similars
PubMed
 1.30n/an/an/an/an/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Displacement of [125I]-Tyr0-sauvagine from human CRF1 receptor expressed in HEK293T cells after 2 hrs by scintillation counting

Bioorg Med Chem Lett 25: 5111-4 (2015)


BindingDB Entry DOI: 10.7270/Q2XW4MM0
More data for this
Ligand-Target Pair