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BDBM50128780 CHEMBL3628736

SMILES: CCCCN(CC)c1cc(C)nc2N(CC(=O)Nc12)c1ccc(C)cc1Br

InChI Key: InChIKey=UISHDOZKMNUZRV-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128780   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))		BDBM50128780
PNG
(CHEMBL3628736)
Show SMILES CCCCN(CC)c1cc(C)nc2N(CC(=O)Nc12)c1ccc(C)cc1Br
Show InChI InChI=1S/C21H27BrN4O/c1-5-7-10-25(6-2)18-12-15(4)23-21-20(18)24-19(27)13-26(21)17-9-8-14(3)11-16(17)22/h8-9,11-12H,5-7,10,13H2,1-4H3,(H,24,27)
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Similars
PubMed
 4.40n/an/an/an/an/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Displacement of [125I]-Tyr0-sauvagine from human CRF1 receptor expressed in HEK293T cells after 2 hrs by scintillation counting

Bioorg Med Chem Lett 25: 5111-4 (2015)


BindingDB Entry DOI: 10.7270/Q2XW4MM0
More data for this
Ligand-Target Pair