BindingDB logo
myBDB logout

null

SMILES: CC(C)c1ccc(N2CC(=O)N(CCF)c3c(cc(C)nc23)N(C)C)c(Br)c1

InChI Key: InChIKey=OYZLFIMAAMUTKT-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128804   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50128804
PNG
(CHEMBL3627731)
Show SMILES CC(C)c1ccc(N2CC(=O)N(CCF)c3c(cc(C)nc23)N(C)C)c(Br)c1
Show InChI InChI=1S/C21H26BrFN4O/c1-13(2)15-6-7-17(16(22)11-15)27-12-19(28)26(9-8-23)20-18(25(4)5)10-14(3)24-21(20)27/h6-7,10-11,13H,8-9,12H2,1-5H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
 59n/an/an/an/an/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Displacement of [125I]-Tyr0-sauvagine from human CRF1 receptor expressed in HEK293T cells after 2 hrs by scintillation counting

Bioorg Med Chem Lett 25: 5111-4 (2015)


Article DOI: 10.1016/j.bmcl.2015.10.010
BindingDB Entry DOI: 10.7270/Q2XW4MM0
More data for this
Ligand-Target Pair