BDBM50128807 CHEMBL3628746

SMILES: CC(C)c1ccc(N2CC(=O)N(CCCCF)c3c(cc(C)nc23)N(C)C)c(Br)c1

InChI Key: InChIKey=SIOIYTNQBWBKQG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128807   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50128807 (CHEMBL3628746) Show SMILES CC(C)c1ccc(N2CC(=O)N(CCCCF)c3c(cc(C)nc23)N(C)C)c(Br)c1 Show InChI InChI=1S/C23H30BrFN4O/c1-15(2)17-8-9-19(18(24)13-17)29-14-21(30)28(11-7-6-10-25)22-20(27(4)5)12-16(3)26-23(22)29/h8-9,12-13,15H,6-7,10-11,14H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Displacement of [125I]-Tyr0-sauvagine from human CRF1 receptor expressed in HEK293T cells after 2 hrs by scintillation counting				Bioorg Med Chem Lett 25: 5111-4 (2015) BindingDB Entry DOI: 10.7270/Q2XW4MM0
					More data for this Ligand-Target Pair