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BDBM50128808 CHEMBL3628854

SMILES: CCN(C)c1cc(C)nc2N(CC(=O)N(CCCCF)c12)c1ccc(cc1Br)C(C)C

InChI Key: InChIKey=WNKKSOFNVWHNQE-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128808   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))		BDBM50128808
PNG
(CHEMBL3628854)
Show SMILES CCN(C)c1cc(C)nc2N(CC(=O)N(CCCCF)c12)c1ccc(cc1Br)C(C)C
Show InChI InChI=1S/C24H32BrFN4O/c1-6-28(5)21-13-17(4)27-24-23(21)29(12-8-7-11-26)22(31)15-30(24)20-10-9-18(16(2)3)14-19(20)25/h9-10,13-14,16H,6-8,11-12,15H2,1-5H3
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PubMed
 14n/an/an/an/an/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Displacement of [125I]-Tyr0-sauvagine from human CRF1 receptor expressed in HEK293T cells after 2 hrs by scintillation counting

Bioorg Med Chem Lett 25: 5111-4 (2015)


BindingDB Entry DOI: 10.7270/Q2XW4MM0
More data for this
Ligand-Target Pair