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BDBM50128841 CHEMBL3629230

SMILES: CC(C(=O)NCc1ccc(cc1-c1ccc(cc1)C(C)(C)C)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1

InChI Key: InChIKey=YJDKAHLIBWOLRQ-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128841   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM50128841
PNG
(CHEMBL3629230)
Show SMILES CC(C(=O)NCc1ccc(cc1-c1ccc(cc1)C(C)(C)C)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1
Show InChI InChI=1/C28H30F4N2O3S/c1-17(19-9-13-25(24(29)14-19)34-38(5,36)37)26(35)33-16-20-8-12-22(28(30,31)32)15-23(20)18-6-10-21(11-7-18)27(2,3)4/h6-15,17,34H,16H2,1-5H3,(H,33,35)
PDB
MMDB

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PC cid
PC sid
UniChem
PubMed
1.10n/an/an/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced activation by FLIPR assay


Bioorg Med Chem 23: 6844-54 (2015)


BindingDB Entry DOI: 10.7270/Q2DZ0B4X
More data for this
Ligand-Target Pair