BDBM50128923 CHEMBL3629501

SMILES: CC(C(=O)NCc1ccc(cc1N1CCN(CC1)c1ccc(C)cc1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1

InChI Key: InChIKey=YOWRVUQLGBUPLP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128923   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50128923 (CHEMBL3629501) Show SMILES CC(C(=O)NCc1ccc(cc1N1CCN(CC1)c1ccc(C)cc1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C29H32F4N4O3S/c1-19-4-9-24(10-5-19)36-12-14-37(15-13-36)27-17-23(29(31,32)33)8-6-22(27)18-34-28(38)20(2)21-7-11-26(25(30)16-21)35-41(3,39)40/h4-11,16-17,20,35H,12-15,18H2,1-3H3,(H,34,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced activation by FLIPR assay				Bioorg Med Chem 23: 6844-54 (2015) BindingDB Entry DOI: 10.7270/Q2DZ0B4X
					More data for this Ligand-Target Pair