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BDBM50128923 CHEMBL3629501

SMILES: CC(C(=O)NCc1ccc(cc1N1CCN(CC1)c1ccc(C)cc1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1

InChI Key: InChIKey=YOWRVUQLGBUPLP-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128923   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM50128923
PNG
(CHEMBL3629501)
Show SMILES CC(C(=O)NCc1ccc(cc1N1CCN(CC1)c1ccc(C)cc1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1
Show InChI InChI=1/C29H32F4N4O3S/c1-19-4-9-24(10-5-19)36-12-14-37(15-13-36)27-17-23(29(31,32)33)8-6-22(27)18-34-28(38)20(2)21-7-11-26(25(30)16-21)35-41(3,39)40/h4-11,16-17,20,35H,12-15,18H2,1-3H3,(H,34,38)
PDB
MMDB

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DrugBank
antibodypedia
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CHEMBL
PC cid
PC sid
UniChem
PubMed
0.700n/an/an/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced activation by FLIPR assay


Bioorg Med Chem 23: 6844-54 (2015)


BindingDB Entry DOI: 10.7270/Q2DZ0B4X
More data for this
Ligand-Target Pair