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SMILES: CC(C(=O)NCc1ccc(cc1N1CCC(CC1)c1ccc(F)cc1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1

InChI Key: InChIKey=WMQSELOGNNSWDT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128988   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50128988
PNG
(CHEMBL3629495)
Show SMILES CC(C(=O)NCc1ccc(cc1N1CCC(CC1)c1ccc(F)cc1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1
Show InChI InChI=1S/C29H30F5N3O3S/c1-18(21-6-10-26(25(31)15-21)36-41(2,39)40)28(38)35-17-22-3-7-23(29(32,33)34)16-27(22)37-13-11-20(12-14-37)19-4-8-24(30)9-5-19/h3-10,15-16,18,20,36H,11-14,17H2,1-2H3,(H,35,38)
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MMDB

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PubMed
 0.900n/an/an/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced activation by FLIPR assay

Bioorg Med Chem 23: 6844-54 (2015)


BindingDB Entry DOI: 10.7270/Q2DZ0B4X
More data for this
Ligand-Target Pair