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BDBM50129028 CHEMBL3627944

SMILES: CC(C(=O)NCc1ccc(cc1OCc1ccc(F)cc1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1

InChI Key: InChIKey=PASMYBFQAZZAIR-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129028   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM50129028
PNG
(CHEMBL3627944)
Show SMILES CC(C(=O)NCc1ccc(cc1OCc1ccc(F)cc1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1
Show InChI InChI=1/C25H23F5N2O4S/c1-15(17-6-10-22(21(27)11-17)32-37(2,34)35)24(33)31-13-18-5-7-19(25(28,29)30)12-23(18)36-14-16-3-8-20(26)9-4-16/h3-12,15,32H,13-14H2,1-2H3,(H,31,33)
PDB
MMDB

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0.5n/an/an/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced activation by FLIPR assay


Bioorg Med Chem 23: 6844-54 (2015)


BindingDB Entry DOI: 10.7270/Q2DZ0B4X
More data for this
Ligand-Target Pair