BDBM50129144 (Z)-5-butylidene-9-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline::5-Butylidene-9-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL65014
SMILES: CCC\C=C1/Oc2ccc(F)cc2-c2ccc3NC(C)(C)C=C(C)c3c12
InChI Key: InChIKey=ZODFDPOWQOXZOI-SCDVKCJHSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Progesterone receptor (Homo sapiens (Human)) | BDBM50129144 ((Z)-5-butylidene-9-fluoro-2,2,4-trimethyl-2,5-dihy...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity to human progesterone receptor | Bioorg Med Chem Lett 13: 2071-4 (2003) BindingDB Entry DOI: 10.7270/Q2SX6DSM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Progesterone receptor (Homo sapiens (Human)) | BDBM50129144 ((Z)-5-butylidene-9-fluoro-2,2,4-trimethyl-2,5-dihy...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Scientific Computing Ltd. Curated by ChEMBL | Assay Description Displacement of [3H]progesterone from Progesterone receptor | J Med Chem 49: 4261-8 (2006) Article DOI: 10.1021/jm060234e BindingDB Entry DOI: 10.7270/Q2V69NB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Progesterone receptor (Homo sapiens (Human)) | BDBM50129144 ((Z)-5-butylidene-9-fluoro-2,2,4-trimethyl-2,5-dihy...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 28 | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Curated by ChEMBL | Assay Description Effective concentration for agonist activity towards human progesterone receptor (hPR) using the cotransfection assay in CV-1 cells | Bioorg Med Chem Lett 13: 2071-4 (2003) BindingDB Entry DOI: 10.7270/Q2SX6DSM | |||||||||||
More data for this Ligand-Target Pair |