BDBM50129202 (S)-2-Amino-4-methyl-pentanoic acid hydroxyamide::(S)-2-amino-N-hydroxy-4-methylpentanamide::CHEMBL303296::L-LEUCYL-HYDROXYLAMINE
SMILES: CC(C)C[C@H](N)C(=O)NO
InChI Key: InChIKey=UJJHPFLWSVFLBE-YFKPBYRVSA-N
Data: 1 KI 1 Kd
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50129202 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Bacterial leucyl aminopeptidase
(Vibrio proteolyticus) | BDBM50129202
((S)-2-Amino-4-methyl-pentanoic acid hydroxyamide |...)Show InChI InChI=1S/C6H14N2O2/c1-4(2)3-5(7)6(9)8-10/h4-5,10H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
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CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| 350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Guilford Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Inhibition of metalloprotease from family M28, Aeromonas proteolytica aminopeptidase |
Bioorg Med Chem Lett 13: 2097-100 (2003)
BindingDB Entry DOI: 10.7270/Q2Z60NF2 |
More data for this Ligand-Target Pair | |
Large neutral amino acids transporter small subunit 1
(Homo sapiens (Human)) | BDBM50129202
((S)-2-Amino-4-methyl-pentanoic acid hydroxyamide |...)Show InChI InChI=1S/C6H14N2O2/c1-4(2)3-5(7)6(9)8-10/h4-5,10H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Patents
Similars
| | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Thermolysin
(Bacillus thermoproteolyticus) | BDBM50129202
((S)-2-Amino-4-methyl-pentanoic acid hydroxyamide |...)Show InChI InChI=1S/C6H14N2O2/c1-4(2)3-5(7)6(9)8-10/h4-5,10H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Patents
Similars
| MMDB PDB Article PubMed
| n/a | n/a | n/a | 1.91E+5 | n/a | n/a | n/a | n/a | n/a |
Harvard University
Curated by ChEMBL
| Assay Description Binding affinity against Thermolysin |
J Med Chem 45: 2770-80 (2002)
Article DOI: 10.1021/jm0105833 BindingDB Entry DOI: 10.7270/Q2MG7S8S |
More data for this Ligand-Target Pair | 3D Structure (crystal) |