BDBM50129405 (R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-2-phenyl-N-(2-piperidin-4-yl-ethyl)-acetamide::CHEMBL67873

SMILES: O[C@@]([C@@H]1CCC(F)(F)C1)(C(=O)NCCC1CCNCC1)c1ccccc1

InChI Key: InChIKey=YDUYOCIXWLWORE-XLIONFOSSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50129405   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129405 ((R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-2-p...) Show SMILES O[C@@]([C@@H]1CCC(F)(F)C1)(C(=O)NCCC1CCNCC1)c1ccccc1 Show InChI InChI=1S/C20H28F2N2O2/c21-19(22)10-6-17(14-19)20(26,16-4-2-1-3-5-16)18(25)24-13-9-15-7-11-23-12-8-15/h1-5,15,17,23,26H,6-14H2,(H,24,25)/t17-,20+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50129405 ((R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-2-p...) Show SMILES O[C@@]([C@@H]1CCC(F)(F)C1)(C(=O)NCCC1CCNCC1)c1ccccc1 Show InChI InChI=1S/C20H28F2N2O2/c21-19(22)10-6-17(14-19)20(26,16-4-2-1-3-5-16)18(25)24-13-9-15-7-11-23-12-8-15/h1-5,15,17,23,26H,6-14H2,(H,24,25)/t17-,20+/m1/s1	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50129405 ((R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-2-p...) Show SMILES O[C@@]([C@@H]1CCC(F)(F)C1)(C(=O)NCCC1CCNCC1)c1ccccc1 Show InChI InChI=1S/C20H28F2N2O2/c21-19(22)10-6-17(14-19)20(26,16-4-2-1-3-5-16)18(25)24-13-9-15-7-11-23-12-8-15/h1-5,15,17,23,26H,6-14H2,(H,24,25)/t17-,20+/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M2 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair