BDBM50129514 CHEMBL71644::{3-(3,4-Dichloro-phenyl)-3-[2-(3-morpholin-4-yl-azetidin-1-yl)-ethyl]-azetidin-1-yl}-phenyl-methanone

SMILES: Clc1ccc(cc1Cl)C1(CCN2CC(C2)N2CCOCC2)CN(C1)C(=O)c1ccccc1

InChI Key: InChIKey=YJJGGKVLMZBFCS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129514   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neurokinin 2 receptor (Homo sapiens (Human))	BDBM50129514 (CHEMBL71644 | {3-(3,4-Dichloro-phenyl)-3-[2-(3-mor...) Show SMILES Clc1ccc(cc1Cl)C1(CCN2CC(C2)N2CCOCC2)CN(C1)C(=O)c1ccccc1 Show InChI InChI=1S/C25H29Cl2N3O2/c26-22-7-6-20(14-23(22)27)25(17-30(18-25)24(31)19-4-2-1-3-5-19)8-9-28-15-21(16-28)29-10-12-32-13-11-29/h1-7,14,21H,8-13,15-18H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligand				Bioorg Med Chem Lett 13: 2211-5 (2003) BindingDB Entry DOI: 10.7270/Q2D799TN
					More data for this Ligand-Target Pair