BDBM50129515 CHEMBL71226::N-{2-(3,4-Dichloro-phenyl)-4-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-pyrrolidin-1-yl]-butyl}-N-methyl-benzamide

SMILES: CN(CC(CCN1CCC(C1)n1c2ccccc2[nH]c1=O)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1

InChI Key: InChIKey=FPXIRXAXVYUYRD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129515   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neurokinin 2 receptor (Homo sapiens (Human))	BDBM50129515 (CHEMBL71226 | N-{2-(3,4-Dichloro-phenyl)-4-[3-(2-o...) Show SMILES CN(CC(CCN1CCC(C1)n1c2ccccc2[nH]c1=O)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1 Show InChI InChI=1S/C29H30Cl2N4O2/c1-33(28(36)20-7-3-2-4-8-20)18-22(21-11-12-24(30)25(31)17-21)13-15-34-16-14-23(19-34)35-27-10-6-5-9-26(27)32-29(35)37/h2-12,17,22-23H,13-16,18-19H2,1H3,(H,32,37)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligand				Bioorg Med Chem Lett 13: 2211-5 (2003) BindingDB Entry DOI: 10.7270/Q2D799TN
					More data for this Ligand-Target Pair