BDBM50129517 CHEMBL307338::N-{2-(3,4-Dichloro-phenyl)-4-[4-hydroxy-4-(1H-imidazol-2-yl)-piperidin-1-yl]-butyl}-N-methyl-benzamide

SMILES: CN(CC(CCN1CCC(O)(CC1)c1ncc[nH]1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1

InChI Key: InChIKey=FWWHFXOSLSCPHG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129517   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neurokinin 2 receptor (Homo sapiens (Human))	BDBM50129517 (CHEMBL307338 | N-{2-(3,4-Dichloro-phenyl)-4-[4-hyd...) Show SMILES CN(CC(CCN1CCC(O)(CC1)c1ncc[nH]1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1 Show InChI InChI=1S/C26H30Cl2N4O2/c1-31(24(33)19-5-3-2-4-6-19)18-21(20-7-8-22(27)23(28)17-20)9-14-32-15-10-26(34,11-16-32)25-29-12-13-30-25/h2-8,12-13,17,21,34H,9-11,14-16,18H2,1H3,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligand				Bioorg Med Chem Lett 13: 2211-5 (2003) BindingDB Entry DOI: 10.7270/Q2D799TN
					More data for this Ligand-Target Pair