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SMILES: [#6]\[#6](-[#6])=[#6]\[#6](=O)-[#8]-c1cccnc1-[#6](=O)-[#7]-c1nccs1

InChI Key: InChIKey=HXMWBPFAEQPIPD-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50129646   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase


(Escherichia coli (strain K12))
BDBM50129646
PNG
(3-Methyl-but-2-enoic acid 2-(thiazol-2-ylcarbamoyl...)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6](=O)-[#8]-c1cccnc1-[#6](=O)-[#7]-c1nccs1
Show InChI InChI=1S/C14H13N3O3S/c1-9(2)8-11(18)20-10-4-3-5-15-12(10)13(19)17-14-16-6-7-21-14/h3-8H,1-2H3,(H,16,17,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.60E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli


J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)
BDBM50129646
PNG
(3-Methyl-but-2-enoic acid 2-(thiazol-2-ylcarbamoyl...)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6](=O)-[#8]-c1cccnc1-[#6](=O)-[#7]-c1nccs1
Show InChI InChI=1S/C14H13N3O3S/c1-9(2)8-11(18)20-10-4-3-5-15-12(10)13(19)17-14-16-6-7-21-14/h3-8H,1-2H3,(H,16,17,19)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 490n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae


J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair