BDBM50129648 3-(4-Methyl-pent-3-enoylamino)-pyridine-2-carboxylic acid thiazol-2-ylamide::CHEMBL328350
SMILES: [#6]\[#6](-[#6])=[#6]/[#6]-[#6](=O)-[#7]-c1cccnc1-[#6](=O)-[#7]-c1nccs1
InChI Key: InChIKey=QLSMZADEWAIARS-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Methionine aminopeptidase 1 (Saccharomyces cerevisiae) | BDBM50129648 (3-(4-Methyl-pent-3-enoylamino)-pyridine-2-carboxyl...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Graduate School of the Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibitory concentration required against Saccharomyces cerevisiae MetAP1 (330 nM) | Bioorg Med Chem Lett 15: 3732-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.055 BindingDB Entry DOI: 10.7270/Q2T1534B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12)) | BDBM50129648 (3-(4-Methyl-pent-3-enoylamino)-pyridine-2-carboxyl...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli | J Med Chem 46: 2631-40 (2003) Article DOI: 10.1021/jm0300532 BindingDB Entry DOI: 10.7270/Q2CF9QTC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methionine aminopeptidase 1 (Saccharomyces cerevisiae) | BDBM50129648 (3-(4-Methyl-pent-3-enoylamino)-pyridine-2-carboxyl...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae | J Med Chem 46: 2631-40 (2003) Article DOI: 10.1021/jm0300532 BindingDB Entry DOI: 10.7270/Q2CF9QTC | |||||||||||
More data for this Ligand-Target Pair |