BDBM50129825 CHEMBL3628793

SMILES: CCOC(=O)Nc1ccc(Nc2ncnc3ccccc23)cc1C

InChI Key: InChIKey=AFOPWEJINDVVQC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50129825   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50129825 (CHEMBL3628793) Show SMILES CCOC(=O)Nc1ccc(Nc2ncnc3ccccc23)cc1C Show InChI InChI=1S/C18H18N4O2/c1-3-24-18(23)22-15-9-8-13(10-12(15)2)21-17-14-6-4-5-7-16(14)19-11-20-17/h4-11H,3H2,1-2H3,(H,22,23)(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Lille Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR-2 after 1 hr using [gamma-32P]ATP				Bioorg Med Chem 23: 7340-7 (2015) BindingDB Entry DOI: 10.7270/Q2BZ67VR
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50129825 (CHEMBL3628793) Show SMILES CCOC(=O)Nc1ccc(Nc2ncnc3ccccc23)cc1C Show InChI InChI=1S/C18H18N4O2/c1-3-24-18(23)22-15-9-8-13(10-12(15)2)21-17-14-6-4-5-7-16(14)19-11-20-17/h4-11H,3H2,1-2H3,(H,22,23)(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Lille Curated by ChEMBL					Assay Description Inhibition of human EGFR after 1 hr using [gamma-32P]ATP				Bioorg Med Chem 23: 7340-7 (2015) BindingDB Entry DOI: 10.7270/Q2BZ67VR
					More data for this Ligand-Target Pair