BindingDB PrimarySearch

null

SMILES: Brc1cccc(NC(=O)Nc2ccc(Oc3ncnc4sc5CCCCc5c34)cc2)c1

InChI Key: InChIKey=GDCAJIUCFRKHLA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50129837
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50129837 (CHEMBL3628811) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Lille Curated by ChEMBL					Assay Description Inhibition of Src (unknown origin) by radiometric protein kinase assay				Bioorg Med Chem 23: 7340-7 (2015) BindingDB Entry DOI: 10.7270/Q2BZ67VR
Univ. Lille Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50129837 (CHEMBL3628811) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Lille Curated by ChEMBL					Assay Description Inhibition of VEGFR1 (unknown origin) by radiometric protein kinase assay				Bioorg Med Chem 23: 7340-7 (2015) BindingDB Entry DOI: 10.7270/Q2BZ67VR
Univ. Lille Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50129837 (CHEMBL3628811) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Lille Curated by ChEMBL					Assay Description Inhibition of VEGFR3 (unknown origin) by radiometric protein kinase assay				Bioorg Med Chem 23: 7340-7 (2015) BindingDB Entry DOI: 10.7270/Q2BZ67VR
Univ. Lille Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50129837 (CHEMBL3628811) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Lille Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta (unknown origin) by radiometric protein kinase assay				Bioorg Med Chem 23: 7340-7 (2015) BindingDB Entry DOI: 10.7270/Q2BZ67VR
Univ. Lille Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50129837 (CHEMBL3628811) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Lille Curated by ChEMBL					Assay Description Inhibition of human EGFR after 1 hr using [gamma-32P]ATP				Bioorg Med Chem 23: 7340-7 (2015) BindingDB Entry DOI: 10.7270/Q2BZ67VR
Univ. Lille Curated by ChEMBL					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50129837 (CHEMBL3628811) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Lille Curated by ChEMBL					Assay Description Inhibition of Raf (unknown origin) by radiometric protein kinase assay				Bioorg Med Chem 23: 7340-7 (2015) BindingDB Entry DOI: 10.7270/Q2BZ67VR
Univ. Lille Curated by ChEMBL					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50129837 (CHEMBL3628811) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Lille Curated by ChEMBL					Assay Description Inhibition of c-MET (unknown origin) by radiometric protein kinase assay				Bioorg Med Chem 23: 7340-7 (2015) BindingDB Entry DOI: 10.7270/Q2BZ67VR
Univ. Lille Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50129837 (CHEMBL3628811) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Lille Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR-2 after 1 hr using [gamma-32P]ATP				Bioorg Med Chem 23: 7340-7 (2015) BindingDB Entry DOI: 10.7270/Q2BZ67VR
Univ. Lille Curated by ChEMBL					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50129837 (CHEMBL3628811) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Lille Curated by ChEMBL					Assay Description Inhibition of c-Kit (unknown origin) by radiometric protein kinase assay				Bioorg Med Chem 23: 7340-7 (2015) BindingDB Entry DOI: 10.7270/Q2BZ67VR
Univ. Lille Curated by ChEMBL					More data for this Ligand-Target Pair