null
SMILES: COc1cc2ncnc(Oc3ccc(NC(=O)Nc4cccc(Br)c4)c(Cl)c3)c2cc1OC
InChI Key: InChIKey=PVSKUFZJHRTTHY-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50129845 (CHEMBL3628806) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Univ. Lille Curated by ChEMBL | Assay Description Inhibition of human EGFR after 1 hr using [gamma-32P]ATP | Bioorg Med Chem 23: 7340-7 (2015) BindingDB Entry DOI: 10.7270/Q2BZ67VR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50129845 (CHEMBL3628806) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Univ. Lille Curated by ChEMBL | Assay Description Inhibition of human recombinant VEGFR-2 after 1 hr using [gamma-32P]ATP | Bioorg Med Chem 23: 7340-7 (2015) BindingDB Entry DOI: 10.7270/Q2BZ67VR | |||||||||||
More data for this Ligand-Target Pair |