BDBM50129940 1-{2-[2-(5-Chloro-pyridin-2-ylamino)-ethylamino]-acetyl}-pyrrolidine-2-carbonitrile::CHEMBL93354

SMILES: Clc1ccc(NCCNCC(=O)N2CCC[C@H]2C#N)nc1

InChI Key: InChIKey=RPJVKSSMOOHWAB-LBPRGKRZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129940   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50129940 (1-{2-[2-(5-Chloro-pyridin-2-ylamino)-ethylamino]-a...) Show SMILES Clc1ccc(NCCNCC(=O)N2CCC[C@H]2C#N)nc1 Show InChI InChI=1S/C14H18ClN5O/c15-11-3-4-13(19-9-11)18-6-5-17-10-14(21)20-7-1-2-12(20)8-16/h3-4,9,12,17H,1-2,5-7,10H2,(H,18,19)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cells				J Med Chem 46: 2774-89 (2003) Article DOI: 10.1021/jm030091l BindingDB Entry DOI: 10.7270/Q20001HR
					More data for this Ligand-Target Pair