BDBM50130088 7-(2-Trifluoromethyl-phenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole::CHEMBL77701

SMILES: FC(F)(F)c1ccccc1-c1cccc2CC3CCNCCN3c12

InChI Key: InChIKey=TVGKTMDQLDJGTD-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50130088   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50130088 (7-(2-Trifluoromethyl-phenyl)-2,3,4,5,11,11a-hexahy...) Show SMILES FC(F)(F)c1ccccc1-c1cccc2CC3CCNCCN3c12 Show InChI InChI=1S/C19H19F3N2/c20-19(21,22)17-7-2-1-5-15(17)16-6-3-4-13-12-14-8-9-23-10-11-24(14)18(13)16/h1-7,14,23H,8-12H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2C receptor using [125I]-DOI radioligand.				Bioorg Med Chem Lett 13: 2369-72 (2003) BindingDB Entry DOI: 10.7270/Q2B857GJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50130088 (7-(2-Trifluoromethyl-phenyl)-2,3,4,5,11,11a-hexahy...) Show SMILES FC(F)(F)c1ccccc1-c1cccc2CC3CCNCCN3c12 Show InChI InChI=1S/C19H19F3N2/c20-19(21,22)17-7-2-1-5-15(17)16-6-3-4-13-12-14-8-9-23-10-11-24(14)18(13)16/h1-7,14,23H,8-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligand.				Bioorg Med Chem Lett 13: 2369-72 (2003) BindingDB Entry DOI: 10.7270/Q2B857GJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50130088 (7-(2-Trifluoromethyl-phenyl)-2,3,4,5,11,11a-hexahy...) Show SMILES FC(F)(F)c1ccccc1-c1cccc2CC3CCNCCN3c12 Show InChI InChI=1S/C19H19F3N2/c20-19(21,22)17-7-2-1-5-15(17)16-6-3-4-13-12-14-8-9-23-10-11-24(14)18(13)16/h1-7,14,23H,8-12H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2C receptor using [125I]-DOI radioligand.				Bioorg Med Chem Lett 13: 2369-72 (2003) BindingDB Entry DOI: 10.7270/Q2B857GJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50130088 (7-(2-Trifluoromethyl-phenyl)-2,3,4,5,11,11a-hexahy...) Show SMILES FC(F)(F)c1ccccc1-c1cccc2CC3CCNCCN3c12 Show InChI InChI=1S/C19H19F3N2/c20-19(21,22)17-7-2-1-5-15(17)16-6-3-4-13-12-14-8-9-23-10-11-24(14)18(13)16/h1-7,14,23H,8-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligand.				Bioorg Med Chem Lett 13: 2369-72 (2003) BindingDB Entry DOI: 10.7270/Q2B857GJ
					More data for this Ligand-Target Pair