BDBM50130404 CHEMBL3633687

SMILES: CCn1cc(CN(Cc2ccc(nc2)-c2cc3nccc(Oc4ccc5oc(Nc6ccc(Cl)cc6)nc5c4)c3s2)C(C)C)nn1

InChI Key: InChIKey=LVCFAFVBQNHCKL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50130404   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50130404 (CHEMBL3633687) Show SMILES CCn1cc(CN(Cc2ccc(nc2)-c2cc3nccc(Oc4ccc5oc(Nc6ccc(Cl)cc6)nc5c4)c3s2)C(C)C)nn1 Show InChI InChI=1S/C34H31ClN8O2S/c1-4-43-20-25(40-41-43)19-42(21(2)3)18-22-5-11-27(37-17-22)32-16-29-33(46-32)31(13-14-36-29)44-26-10-12-30-28(15-26)39-34(45-30)38-24-8-6-23(35)7-9-24/h5-17,20-21H,4,18-19H2,1-3H3,(H,38,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin)				Eur J Med Chem 103: 105-22 (2015) BindingDB Entry DOI: 10.7270/Q2P84DQG
					More data for this Ligand-Target Pair