BDBM50130409 CHEMBL3633691

SMILES: CCS(=O)(=O)c1ccc(OC)c(Nc2cn(nn2)-c2ccc(NC(N)=O)c(c2)-c2cccc3ccccc23)c1

InChI Key: InChIKey=FYRQMZXGASEEOK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50130409   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50130409 (CHEMBL3633691) Show SMILES CCS(=O)(=O)c1ccc(OC)c(Nc2cn(nn2)-c2ccc(NC(N)=O)c(c2)-c2cccc3ccccc23)c1 Show InChI InChI=1S/C28H26N6O4S/c1-3-39(36,37)20-12-14-26(38-2)25(16-20)30-27-17-34(33-32-27)19-11-13-24(31-28(29)35)23(15-19)22-10-6-8-18-7-4-5-9-21(18)22/h4-17,30H,3H2,1-2H3,(H3,29,31,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant VEGFR2 kinase expressed in Sf9 insect cells by radiometric protein kinase assay				Eur J Med Chem 103: 105-22 (2015) BindingDB Entry DOI: 10.7270/Q2P84DQG
					More data for this Ligand-Target Pair