BDBM50130510 CHEMBL3632698
SMILES: COc1cc(ccc1COCC(O)CN1CCC(CC1)C(=O)Nc1ccccc1)C(F)(F)F
InChI Key: InChIKey=IDTATHNFNARTJV-UHFFFAOYSA-N
Data: 5 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human)) | BDBM50130510 (CHEMBL3632698) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assay | Bioorg Med Chem Lett 25: 5419-23 (2015) BindingDB Entry DOI: 10.7270/Q2930W06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel alpha subunit (Homo sapiens (Human)) | BDBM50130510 (CHEMBL3632698) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human NaV1.1 by IonWorks quattro automated electrophysiology assay | Bioorg Med Chem Lett 25: 5419-23 (2015) BindingDB Entry DOI: 10.7270/Q2930W06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-gated sodium channel alpha subunit Nav1.1 (Mus musculus) | BDBM50130510 (CHEMBL3632698) | GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd Curated by ChEMBL | Assay Description Inhibition of mouse NaV1.1 by IonWorks quattro automated electrophysiology assay | Bioorg Med Chem Lett 25: 5419-23 (2015) BindingDB Entry DOI: 10.7270/Q2930W06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 9 subunit alpha (Mus musculus) | BDBM50130510 (CHEMBL3632698) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd Curated by ChEMBL | Assay Description Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assay | Bioorg Med Chem Lett 25: 5419-23 (2015) BindingDB Entry DOI: 10.7270/Q2930W06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human)) | BDBM50130510 (CHEMBL3632698) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human NaV1.5 by IonWorks quattro automated electrophysiology assay | Bioorg Med Chem Lett 25: 5419-23 (2015) BindingDB Entry DOI: 10.7270/Q2930W06 | |||||||||||
More data for this Ligand-Target Pair |