BDBM50130697 CHEMBL3632740

SMILES: Cc1c(sc2ncnc(Nc3ccc(F)cc3)c12)C(O)=O

InChI Key: InChIKey=PCNMAFAGYQATHH-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50130697   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50130697 (CHEMBL3632740) Show SMILES Cc1c(sc2ncnc(Nc3ccc(F)cc3)c12)C(O)=O Show InChI InChI=1S/C14H10FN3O2S/c1-7-10-12(18-9-4-2-8(15)3-5-9)16-6-17-13(10)21-11(7)14(19)20/h2-6H,1H3,(H,19,20)(H,16,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	164	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of human Mnk2a using TAMRA-labeled eIF4E peptide as substrate incubated for 10 mins followed by addition of ATP measured after 90 mins by ...				Eur J Med Chem 103: 539-50 (2015) BindingDB Entry DOI: 10.7270/Q2S184B8
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50130697 (CHEMBL3632740) Show SMILES Cc1c(sc2ncnc(Nc3ccc(F)cc3)c12)C(O)=O Show InChI InChI=1S/C14H10FN3O2S/c1-7-10-12(18-9-4-2-8(15)3-5-9)16-6-17-13(10)21-11(7)14(19)20/h2-6H,1H3,(H,19,20)(H,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of Mnk1a (unknown origin) using TAMRA-labeled eIF4E peptide as substrate incubated for 10 mins followed by addition of ATP measured after ...				Eur J Med Chem 103: 539-50 (2015) BindingDB Entry DOI: 10.7270/Q2S184B8
					More data for this Ligand-Target Pair