BDBM50130698 CHEMBL3632741
SMILES: Cc1c(sc2ncnc(Nc3ccc(F)cc3C)c12)C(O)=O
InChI Key: InChIKey=ZGSDVEBXWRCHHZ-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM50130698 (CHEMBL3632741) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of South Australia Curated by ChEMBL | Assay Description Inhibition of human Mnk2a using TAMRA-labeled eIF4E peptide as substrate incubated for 10 mins followed by addition of ATP measured after 90 mins by ... | Eur J Med Chem 103: 539-50 (2015) BindingDB Entry DOI: 10.7270/Q2S184B8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human)) | BDBM50130698 (CHEMBL3632741) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of South Australia Curated by ChEMBL | Assay Description Inhibition of Mnk1a (unknown origin) using TAMRA-labeled eIF4E peptide as substrate incubated for 10 mins followed by addition of ATP measured after ... | Eur J Med Chem 103: 539-50 (2015) BindingDB Entry DOI: 10.7270/Q2S184B8 | |||||||||||
More data for this Ligand-Target Pair |