BDBM50130713 CHEMBL326801::Thioacetic acid S-(2-benzylcarbamoyl-propyl) ester
SMILES: CC(CSC(C)=O)C(=O)NCc1ccccc1
InChI Key: InChIKey=ULQOPCYTXCELHU-UHFFFAOYSA-N
Data: 5 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neprilysin (Homo sapiens (Human)) | BDBM50130713 (CHEMBL326801 | Thioacetic acid S-(2-benzylcarbamoy...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences Curated by ChEMBL | Assay Description Inhibitory activity against neutral endopeptidase (NEP) from human blood serum | J Med Chem 46: 3326-32 (2003) Article DOI: 10.1021/jm021089h BindingDB Entry DOI: 10.7270/Q2K07512 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat)) | BDBM50130713 (CHEMBL326801 | Thioacetic acid S-(2-benzylcarbamoy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences Curated by ChEMBL | Assay Description Inhibitory activity against neutral endopeptidase (NEP) from rat cortex brain membrane | J Med Chem 46: 3326-32 (2003) Article DOI: 10.1021/jm021089h BindingDB Entry DOI: 10.7270/Q2K07512 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin-converting enzyme (Rattus norvegicus) | BDBM50130713 (CHEMBL326801 | Thioacetic acid S-(2-benzylcarbamoy...) | KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences Curated by ChEMBL | Assay Description Inhibitory activity against Angiotensin I converting enzyme (ACE) from rat cortex brain membrane | J Med Chem 46: 3326-32 (2003) Article DOI: 10.1021/jm021089h BindingDB Entry DOI: 10.7270/Q2K07512 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin-converting enzyme (Homo sapiens (Human)) | BDBM50130713 (CHEMBL326801 | Thioacetic acid S-(2-benzylcarbamoy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences Curated by ChEMBL | Assay Description Inhibitory activity against Angiotensin I converting enzyme (ACE) from bovine kidney | J Med Chem 46: 3326-32 (2003) Article DOI: 10.1021/jm021089h BindingDB Entry DOI: 10.7270/Q2K07512 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin-converting enzyme (Homo sapiens (Human)) | BDBM50130713 (CHEMBL326801 | Thioacetic acid S-(2-benzylcarbamoy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences Curated by ChEMBL | Assay Description Inhibitory activity against Angiotensin I converting enzyme (ACE) from human blood serum | J Med Chem 46: 3326-32 (2003) Article DOI: 10.1021/jm021089h BindingDB Entry DOI: 10.7270/Q2K07512 | |||||||||||
More data for this Ligand-Target Pair |