BDBM50130929 CHEMBL3633189
SMILES: NC(=N)c1ccc(Nc2ncnc(Nc3ccc(cc3)C#N)c2[N+]([O-])=O)cc1
InChI Key: InChIKey=SHIUJOLGVWYPDY-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein-arginine N-methyltransferase 1 (Homo sapiens (Human)) | BDBM50130929 (CHEMBL3633189) | PDB B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University Curated by ChEMBL | Assay Description Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1 | Bioorg Med Chem Lett 25: 5449-53 (2015) BindingDB Entry DOI: 10.7270/Q2R2136F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-arginine N-methyltransferase 1 (Homo sapiens (Human)) | BDBM50130929 (CHEMBL3633189) | PDB B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University Curated by ChEMBL | Assay Description Inhibition of PRMT1 (unknown origin) using biotinylated histone H4-derived peptide as substrate after 60 mins by AlphaLISA assay | Bioorg Med Chem Lett 25: 5449-53 (2015) BindingDB Entry DOI: 10.7270/Q2R2136F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human)) | BDBM50130929 (CHEMBL3633189) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University Curated by ChEMBL | Assay Description Inhibition of PRMT4 (unknown origin) using biotinylated histone H4-derived peptide as substrate after 60 mins by AlphaLISA assay | Bioorg Med Chem Lett 25: 5449-53 (2015) BindingDB Entry DOI: 10.7270/Q2R2136F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein arginine N-methyltransferase 6 (Homo sapiens (Human)) | BDBM50130929 (CHEMBL3633189) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University Curated by ChEMBL | Assay Description Inhibition of PRMT6 (unknown origin) using biotinylated histone H4-derived peptide as substrate after 60 mins by AlphaLISA assay | Bioorg Med Chem Lett 25: 5449-53 (2015) BindingDB Entry DOI: 10.7270/Q2R2136F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein arginine N-methyltransferase 5 (Homo sapiens (Human)) | BDBM50130929 (CHEMBL3633189) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University Curated by ChEMBL | Assay Description Inhibition of PRMT5 (unknown origin) using biotinylated histone H4-derived peptide as substrate after 60 mins by AlphaLISA assay | Bioorg Med Chem Lett 25: 5449-53 (2015) BindingDB Entry DOI: 10.7270/Q2R2136F | |||||||||||
More data for this Ligand-Target Pair |