BDBM50130959 2-(2,4-Dichloro-phenyl)-5-dipropylamino-3-ethyl-6-methyl-3H-pyrimidin-4-one::CHEMBL84339

SMILES: CCCN(CCC)c1c(C)nc(-c2ccc(Cl)cc2Cl)n(CC)c1=O

InChI Key: InChIKey=CZZWROMXVJEUPV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50130959   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50130959 (2-(2,4-Dichloro-phenyl)-5-dipropylamino-3-ethyl-6-...) Show SMILES CCCN(CCC)c1c(C)nc(-c2ccc(Cl)cc2Cl)n(CC)c1=O Show InChI InChI=1S/C19H25Cl2N3O/c1-5-10-23(11-6-2)17-13(4)22-18(24(7-3)19(17)25)15-9-8-14(20)12-16(15)21/h8-9,12H,5-7,10-11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Affinity for Corticotropin releasing factor receptor 1 on IMR-32 (human neuroblastoma) cells by [125I]-sauvagine displacement.				Bioorg Med Chem Lett 13: 2497-500 (2003) BindingDB Entry DOI: 10.7270/Q2C53K72
					More data for this Ligand-Target Pair