BDBM50130973 5-Dipropylamino-3,6-diethyl-2-(2-methoxy-4,6-dimethyl-phenyl)-3H-pyrimidin-4-one::CHEMBL313479
SMILES: CCCN(CCC)c1c(CC)nc(-c2c(C)cc(C)cc2OC)n(CC)c1=O
InChI Key: InChIKey=WCQJNSSUUQDQQR-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Corticotropin releasing factor receptor 1 (Homo sapiens (Human)) | BDBM50130973 (5-Dipropylamino-3,6-diethyl-2-(2-methoxy-4,6-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation Curated by ChEMBL | Assay Description Affinity for Corticotropin releasing factor receptor 1 on IMR-32 (human neuroblastoma) cells by [125I]-sauvagine displacement. | Bioorg Med Chem Lett 13: 2497-500 (2003) BindingDB Entry DOI: 10.7270/Q2C53K72 | |||||||||||
More data for this Ligand-Target Pair |