BDBM50131044 13H-Indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5-one::CHEMBL413956
SMILES: O=c1c2ccccc2[nH]c2c3nc4ccccc4c3ccn12
InChI Key: InChIKey=YSBDHHSWPXFVSR-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 1B1 (Homo sapiens (Human)) | BDBM50131044 (13H-Indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5-one...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Institute of Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of Cytochrome P450 1B1 enzyme in bacterial membrane expressing human P450s | Bioorg Med Chem Lett 13: 2535-8 (2003) BindingDB Entry DOI: 10.7270/Q2805341 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A (Homo sapiens (Human)) | BDBM50131044 (13H-Indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5-one...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Institute of Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of Cytochrome P450 1A2 enzyme in bacterial membrane expressing human P450s | Bioorg Med Chem Lett 13: 2535-8 (2003) BindingDB Entry DOI: 10.7270/Q2805341 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A1 (Homo sapiens (Human)) | BDBM50131044 (13H-Indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5-one...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Institute of Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of Cytochrome P450 1A1 enzyme in bacterial membrane expressing human P450s | Bioorg Med Chem Lett 13: 2535-8 (2003) BindingDB Entry DOI: 10.7270/Q2805341 | |||||||||||
More data for this Ligand-Target Pair |