BDBM50131122 2-(Pyrimidin-4-ylamino)-benzothiazole-6-carboxylic acid (2-chloro-6-methyl-phenyl)-amide::CHEMBL408849

SMILES: Cc1cccc(Cl)c1NC(=O)c1ccc2nc(Nc3ccncn3)sc2c1

InChI Key: InChIKey=IOOBCJICSNTUDK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50131122   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50131122 (2-(Pyrimidin-4-ylamino)-benzothiazole-6-carboxylic...) Show SMILES Cc1cccc(Cl)c1NC(=O)c1ccc2nc(Nc3ccncn3)sc2c1 Show InChI InChI=1S/C19H14ClN5OS/c1-11-3-2-4-13(20)17(11)25-18(26)12-5-6-14-15(9-12)27-19(23-14)24-16-7-8-21-10-22-16/h2-10H,1H3,(H,25,26)(H,21,22,23,24)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human p56 Lck tyrosine kinase				Bioorg Med Chem Lett 13: 2587-90 (2003) BindingDB Entry DOI: 10.7270/Q2FX78V4
					More data for this Ligand-Target Pair