BDBM50131152 2-[2-(2-Hydroxy-2-methyl-propylamino)-6-methyl-pyrimidin-4-ylamino]-benzothiazole-6-carboxylic acid (2-chloro-6-methyl-phenyl)-amide::CHEMBL87102

SMILES: Cc1cc(Nc2nc3ccc(cc3s2)C(=O)Nc2c(C)cccc2Cl)nc(NCC(C)(C)O)n1

InChI Key: InChIKey=QXCJTHGNYGKRDA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50131152   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50131152 (2-[2-(2-Hydroxy-2-methyl-propylamino)-6-methyl-pyr...) Show SMILES Cc1cc(Nc2nc3ccc(cc3s2)C(=O)Nc2c(C)cccc2Cl)nc(NCC(C)(C)O)n1 Show InChI InChI=1S/C24H25ClN6O2S/c1-13-6-5-7-16(25)20(13)31-21(32)15-8-9-17-18(11-15)34-23(28-17)30-19-10-14(2)27-22(29-19)26-12-24(3,4)33/h5-11,33H,12H2,1-4H3,(H,31,32)(H2,26,27,28,29,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human p56 Lck tyrosine kinase				Bioorg Med Chem Lett 13: 2587-90 (2003) BindingDB Entry DOI: 10.7270/Q2FX78V4
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