BDBM50131181 2-(3-Chloro-benzyl)-5-(2,4-dichloro-phenyl)-2H-[1,2,4]triazole-3-thiol::CHEMBL82566

SMILES: Clc1cccc(Cn2nc([nH]c2=S)-c2ccc(Cl)cc2Cl)c1

InChI Key: InChIKey=NLSGPSLKBTYDDS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50131181   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50131181 (2-(3-Chloro-benzyl)-5-(2,4-dichloro-phenyl)-2H-[1,...) Show SMILES Clc1cccc(Cn2nc([nH]c2=S)-c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C15H10Cl3N3S/c16-10-3-1-2-9(6-10)8-21-15(22)19-14(20-21)12-5-4-11(17)7-13(12)18/h1-7H,8H2,(H,19,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibition of binding of [125I]-IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranes				Bioorg Med Chem Lett 13: 2625-8 (2003) BindingDB Entry DOI: 10.7270/Q2B56J5K
					More data for this Ligand-Target Pair