BDBM50131192 2-Benzyl-5-(2-bromo-phenyl)-2H-[1,2,4]triazole-3-thiol::CHEMBL313556

SMILES: Brc1ccccc1-c1nn(Cc2ccccc2)c(=S)[nH]1

InChI Key: InChIKey=FKZLBZDXOZJIIY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50131192   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50131192 (2-Benzyl-5-(2-bromo-phenyl)-2H-[1,2,4]triazole-3-t...) Show SMILES Brc1ccccc1-c1nn(Cc2ccccc2)c(=S)[nH]1 Show InChI InChI=1S/C15H12BrN3S/c16-13-9-5-4-8-12(13)14-17-15(20)19(18-14)10-11-6-2-1-3-7-11/h1-9H,10H2,(H,17,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibition of binding of [125I]-IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranes				Bioorg Med Chem Lett 13: 2625-8 (2003) BindingDB Entry DOI: 10.7270/Q2B56J5K
					More data for this Ligand-Target Pair