BDBM50131202 5-(2,4-Dichloro-phenyl)-2-(3-methoxy-benzyl)-2H-[1,2,4]triazole-3-thiol::CHEMBL315206

SMILES: COc1cccc(Cn2nc([nH]c2=S)-c2ccc(Cl)cc2Cl)c1

InChI Key: InChIKey=RGXGUTSWTNWGMM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50131202   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50131202 (5-(2,4-Dichloro-phenyl)-2-(3-methoxy-benzyl)-2H-[1...) Show SMILES COc1cccc(Cn2nc([nH]c2=S)-c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C16H13Cl2N3OS/c1-22-12-4-2-3-10(7-12)9-21-16(23)19-15(20-21)13-6-5-11(17)8-14(13)18/h2-8H,9H2,1H3,(H,19,20,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibition of binding of [125I]-IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranes				Bioorg Med Chem Lett 13: 2625-8 (2003) BindingDB Entry DOI: 10.7270/Q2B56J5K
					More data for this Ligand-Target Pair