BDBM50131373 CHEMBL3634777

SMILES: Fc1ccccc1-c1n[nH]c2cnc(cc12)-c1cnccc1O[C@@H]1CCCNC1

InChI Key: InChIKey=FHAPDLVADXCIGY-CQSZACIVSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131373   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50131373 (CHEMBL3634777) Show SMILES Fc1ccccc1-c1n[nH]c2cnc(cc12)-c1cnccc1O[C@@H]1CCCNC1 |r| Show InChI InChI=1S/C22H20FN5O/c23-18-6-2-1-5-15(18)22-16-10-19(26-13-20(16)27-28-22)17-12-25-9-7-21(17)29-14-4-3-8-24-11-14/h1-2,5-7,9-10,12-14,24H,3-4,8,11H2,(H,27,28)/t14-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of Pim3 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins				Bioorg Med Chem Lett 25: 5258-64 (2015) BindingDB Entry DOI: 10.7270/Q2TT4SR7
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50131373 (CHEMBL3634777) Show SMILES Fc1ccccc1-c1n[nH]c2cnc(cc12)-c1cnccc1O[C@@H]1CCCNC1 |r| Show InChI InChI=1S/C22H20FN5O/c23-18-6-2-1-5-15(18)22-16-10-19(26-13-20(16)27-28-22)17-12-25-9-7-21(17)29-14-4-3-8-24-11-14/h1-2,5-7,9-10,12-14,24H,3-4,8,11H2,(H,27,28)/t14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of Pim2 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins				Bioorg Med Chem Lett 25: 5258-64 (2015) BindingDB Entry DOI: 10.7270/Q2TT4SR7
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50131373 (CHEMBL3634777) Show SMILES Fc1ccccc1-c1n[nH]c2cnc(cc12)-c1cnccc1O[C@@H]1CCCNC1 |r| Show InChI InChI=1S/C22H20FN5O/c23-18-6-2-1-5-15(18)22-16-10-19(26-13-20(16)27-28-22)17-12-25-9-7-21(17)29-14-4-3-8-24-11-14/h1-2,5-7,9-10,12-14,24H,3-4,8,11H2,(H,27,28)/t14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of Pim1 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins				Bioorg Med Chem Lett 25: 5258-64 (2015) BindingDB Entry DOI: 10.7270/Q2TT4SR7
					More data for this Ligand-Target Pair